22 Nisan 2011 Cuma

Apolipoprotein E4 - Cause of Ageing, Alzheimer

This protein has an association with nerve cell that is responsible for ageing faster than the other cells. One - fourth of people who carry this gene have risk of Alzheimer, cardiovascular disease and amnesia (memory loss).

North Carolina's Duke University Medical Center is the place where researches had been done. According to the leader of study researchers say that The earlist and most consistent actions are happening in the frontal lobe of brain. Therefore, most of mental symptoms of ageing is resulted from a problem in the frontal lobe of brain.

To explain the studies, test subjects are aged between 55 and 85. They were seperated into two groups, based on whether carried APOE4 or not. They were taken memory tests to obtain their NAA ( N-acetylsparate), a brain cell conceived to be associated with nerve cells and thus with mental specificasion. A undergroup of the participants was given more memory test again after two years. The studies indicated that those who have lower NAA levels before had greater loss of short term memory and manimg abilities.Those who dont have APOE4 showed great progress than the others within this protein. It was the big progress in the science.


They learned what the cause of ageing, so perhaps one day will be develop treatment for these diseases.

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